Jason and Danny are forever haunted by the murder of their bank robber father which left their family desolate. When the boys' mother comes home with a new prescription painkiller, the two are introduced to one tiny pill that would forever change their lives. As they quickly find themselves at the height of Boston's Oxycontin drug trade, the brothers and their ferociously loyal crew try to hold stable ground as their lives, and the lives of everyone around them, begin to crumble.